SRCIN1 and osteosarcoma: Wang et al., for example, determined that SRCIN1 was able to enhance in vitro E-cadherin expression and to thereby suppress osteosarcoma cell growth [15], while Sun et al. ascertained that miR-181a was capable to suppress SRCIN1 expression in colorectal cancer cells, thereby modulating SRC/VEGF signaling to influence angiogenic activity [16].