The previous research results of our group showed that the expression of TrkB mRNA and protein was overexpressed in tumor tissues, and the high expression of TrkB significantly reduced the overall survival time of patients, which is closely related to clinical staging, lymph node metastasis, and smoking history, which can be an independent prognostic indicator for laryngeal cancer. The gene discussed is NTRK2; the disease is metastatic malignant neoplasm in the lymph nodes.