Tang Jian et al. [21] found that the proliferation of human colon cancer HT-29 cells can be inhibited by inhibiting the PI3K/AKT signaling pathway; this is achieved by inhibiting the downstream expression of the P-glycoprotein transduction pathway and blocking the cell cycle in the G1 phase. The gene discussed is ABCB1; the disease is malignant colon neoplasm.