Consistently, the treatment of two FGFR3-mutated PDXs, one Ba/Sq and one LumP, both presenting high expression levels of FGFR3 protein compared to other non-mutated PDXs, with a pan-FGFR-inhibitor (BGJ398) (Supplementary Figure 3A) only reduced tumor growth (Supplementary Figure 3B). This evidence concerns the gene FGFR3 and neoplasm.