SP1 and retinoblastoma: 61 found that LINC00152, which is activated by Sp1, can sponge miR-30d, thus significantly increasing the expression of SOX9 and zinc finger E-box-binding homeobox 2 (ZEB2), inducing EMT, and promoting the invasion and metastasis of retinoblastoma cells (61). LINC00152 regulates the expression of YAP1 in retinoblastoma cells by sponging miR-613, thus promoting proliferation, invasion, apoptosis, autophagy, and chemical resistance of retinoblastoma cells (62).