Univariate and multivariate Cox regression analyses were performed to explore whether three coexisting genes (ABCC5, DHODH, and TUBG1) were associated with the prognosis of HCC, and the results showed that ABCC5 and TUBG1 were independent risk factors for the prognosis of HCC (HR>1, P<0.05) (Figure 6A). The gene discussed is ABCC5; the disease is hepatocellular carcinoma.