Therefore, we conclude that these data together with the BBB penetration (Table 2), Kp,uu value in mice (0.23), in vitro data (Figure 1), and exclusion as a substrate of P-glycoprotein and BCRP shows enough evidence of GLR2007’s potential efficacy for the possible treatment of GBM to support further investigation of GLR2007 through more research and clinical trials (19). The gene discussed is ABCB1; the disease is glioblastoma.