Eventually, Yap1/TAZ interact with other transcription factors such as TEA domain (TEAD), Runt-related transcription factor (RUNX), and SMAD to induce the expression of genes such as CTGF, Survivin, CYR61, and JAG1, that facilitate migration and proliferation of tumor cells, and inhibition of apoptosis (5–12). Here, YAP1 is linked to neoplasm.