Otherwise, actinin alpha 1 (ACTN1) expression, acyl-CoA dehydrogenase Long-chain (ACADL)/YAP, and YAP/Forkhead Box M1 (FOXM1) are proposed targets for preventing tumor growth and early recurrence of HCC (74–76) (Table 1). The gene discussed is ACTN1; the disease is hepatocellular carcinoma.