We applied the multivariate Cox regression analysis to investigate the prognostic power of the signature, and the result revealed that the expression ofMLLT11 hazard ratios (HR) = 0.47, p < 0.026) is an independent prognostic biomarker for glioma patients after adjusting for age, gender, IDH, MGMT promoter, Telomerase reverse transcriptase (TERT) promoter, and 1p19q codeletion status (Figure 3I). Here, MGMT is linked to central nervous system cancer.