In the analysis of tumor tissue cells, the tendencies were more obvious: the CD4+/CD8+ ratio in the metastasis group and nonmetastasis group was 1.66 ± 0.38 and 1.18 ± 0.29, respectively (Figure 8B, P < 0.001), and the CCR5+/CD4+ ratio was 0.46 ± 0.08 and 0.18 ± 0.04, respectively (P < 0.001) (Figure 8D). Here, CD8A is linked to neoplasm.