CD4 and metastatic malignant neoplasm in the lymph nodes: The results showed that an increase in the CD4+CD25+Foxp3+(Treg)/CCR5+ cell ratio was closely related to the invasiveness of tumors: the Treg/CCR5 ratio in the lymph node metastasis group and nonmetastasis group was 0.028 ± 0.007 and 0.024 ± 0.003, respectively, P = 0.035.