Additional genes identified, including HSD17B2, CYP27B1, ZFP36L1, EGR1, VDR, CAPN1, FOXC1, EREG, GATA6, ALOX15B, LIPE, GJA1, ZFP36, CDH3, and RUNX (Figure 1E) have been implicated in PCa progression (27–38). Here, EGR1 is linked to posterior cortical atrophy.