Additional genes identified, including HSD17B2, CYP27B1, ZFP36L1, EGR1, VDR, CAPN1, FOXC1, EREG, GATA6, ALOX15B, LIPE, GJA1, ZFP36, CDH3, and RUNX (Figure 1E) have been implicated in PCa progression (27–38). This evidence concerns the gene HSD17B2 and posterior cortical atrophy.