Additional genes identified, including HSD17B2, CYP27B1, ZFP36L1, EGR1, VDR, CAPN1, FOXC1, EREG, GATA6, ALOX15B, LIPE, GJA1, ZFP36, CDH3, and RUNX (Figure 1E) have been implicated in PCa progression (27–38). The gene discussed is CYP27B1; the disease is posterior cortical atrophy.