The expression of most of the genes associated with poor prognosis in GBM such as PAK1, DDB2, SLC2A3, TNFRSF1A, MAFF, and DKK3 showed significant, negative correlations with CD8+ T immune cell infiltrations in GBM tissues (Figures 3A, D). The gene discussed is TNFRSF1A; the disease is glioblastoma.