We executed meta-analysis on the correlation between 12 variants of ERCC4 and the risk of 13 types of cancer, and four SNPs (rs744154, rs1800067, rs2276466, and rs1799801) were figured out to be significantly associated with risk of three cancers (bladder cancer, gastric cancer, and glioma) (Table 1). Here, ERCC4 is linked to urinary bladder cancer.