In this present study, we evaluated the associations between 78 SNPs in ERCC4 and ERCC5 and 22 cancer risks based on each SNP extracted from one data source, and then calculated the FPRP values of significant findings; two associations (rs2276466 with gastric cancer risk in Asians, rs2094258 with neuroblastoma in Asians) were affirmed as strong evidence (Supplementary Table S8). This evidence concerns the gene ERCC4 and neuroblastoma.