There are several different ROS1 rearrangements, including CD74-ROS1, SLC34A2-ROS1, YWHAE-ROS1, TFG-ROS1, and CEP85L-ROS1, but CD74-ROS1 (44%) is the most common ROS1 rearrangement found in NSCLC patients (29). Here, CD74 is linked to non-small cell lung carcinoma.