ITGA6 and lung cancer: Lung cancer stem cells (LCSCs) with high chemo-resistance were obtained from the NSCLC patients; the subpopulation of LCSCs show self-renewal, resistance, invasion, and tumorigenic potential in the in vitro experiments, and the CDKN1A, ITGA6, and SNAI1that were selected by different expression levels between LCSCs and the adherent-cultured cells could become biomarkers for indicating the different stages of lung cancer in patients (74).