To investigate whether the microbiota influenced the local migration of NK cells and CD8+T cells to lung tissues by influencing the expression of the CXCL9/10-CXCR3 axis during the progression of lung cancer in mice, we evaluated CXCL9, CXCL10, and CXCR3 mRNA levels in lung tissues of Abt-WT and Kras-mutated mice and paired controls at stage 1 and 3 tumours. The gene discussed is CD8A; the disease is neoplasm.