In the current study, we found that the expressions of CXCL9 and CXCR3 mRNA increased significantly in the lungs of Abt-Kras mice compared to paired controls as tumour progressed, and this may be the main reason for the constant amount of NK cells and CD8+T cells in their lung (Figure 4). The gene discussed is CXCR3; the disease is neoplasm.