Five regulators of this pathway (TAOK1, TAOK2, MOB1A/B, and LATS1) were significantly suppressed in chordoma samples and two of them are predicted targets for upregulated miRNAs (TAOK1 for miR-142, and MOB1B for miR-148a and miR-182). The gene discussed is MOB1B; the disease is chordoma.