As a novel lncRNA, benzodiazapine receptor associated protein 1 antisense RNA 1 (BZRAP1-AS1), also named TSPOAP1-AS1, was mentioned firstly in Alzheimer’s disease (Jun et al., 2017; Witoelar et al., 2018; Tan et al., 2021a). Here, TSPOAP1 is linked to early-onset autosomal dominant Alzheimer disease.