Proteases, including urokinase plasminogen activator, which promotes tumor cellular invasion, and cathepsin D, and adhesion modulators, including vimentin, galectin 3-binding protein, and annexin A1, have additionally been determined in tumor-derived exosomes (Harris et al., 2015); miRNAs and different nucleic acids, that may result in malignant adjustments in target cells, had been identified in tumor cellular exosomes (Melo et al., 2014). Here, VIM is linked to neoplasm.