SLC1A5 and neoplasm: SNAT1 (SLC38A1) is important in glutamine uptake by neuronal cells and ASCT2 (SLC1A5) is essential for glutamine uptake by rapidly growing epithelial cells and tumour cells in culture; the brush border membrane transporter B0 AT1 (SLC6A19) facilitates the uptake of glutamine across the kidney and intestinal brush border (McGivan and Bungard, 2007).