SMARCA2 and Intellectual disability: Heterozygous missense mutations in SWI/SNF-related matrix associated, actin-dependent regulator of chromatin, subfamily A, member 2 (SMARCA2) cause Nicolaides–Baraitser syndrome, characterized by distal-limb anomalies, distinctive facial morphology, intellectual disability, and sparse hair (Van Houdt et al., 1997).