AR: Allergic rhinitis; M PAR: Mild persistent allergic rhinitis; M/S PAR: Moderate to Severe persistent allergic rhinitis; SPT: skin prick test; Th1: T helper1; IL-4: Interleukin-4; TGF-β1: Transforming growth factor-1; TNSS: Total Nasal Syndrome Score; CBC: complete blood count. The gene discussed is TGFB1; the disease is allergic rhinitis.