Ebner et al reported that the 12.1% of 2992 patients who had <10 nodes retrieved in their study following ALND were older, postmenopausal, had higher proportion of Luminal A tumors with lower hormone receptor positivity and lower tumor grade.32 They therefore submitted that the lymph node count is probably arbitrary as there was no significant difference in the survival and recurrence outcomes of breast cancer patients with <10 and >10 retrieved axillary nodes. Here, NR4A1 is linked to breast cancer.