IFNA1 and asthma: Reciprocally, the attenuation of Th1 immune response in asthma was not supported by other work, in which some have shown induction of type1 or type2 IFN at similar levels in asthmatic patients and controls (98, 146, 147), whereas others even have shown excessive IFN-associated response in asthmatics compared with controls (148, 149).