The clusters were listed from 1998 to 2016: “postpartum” (Cluster 9, n=54), “interferon-alpha” (Cluster 10 n=46), “apoptosis” (Cluster 8, n=59), “regulatory t cells” (Cluster 2, n=101), “hashimoto’s encephalopathy” (Cluster 5, n=95), “CCL2” (Cluster 11, n=26), “CTLA-4” (Cluster 1, n=107), “thyroid cancer” (Cluster 7, n=67), “IgG4” (Cluster 6, n=82), “oxidative stress” (Cluster 0, n=128), “papillary thyroid cancer” (Cluster 4 n=96), and “Vitamin D” (Cluster 3, n=98). The gene discussed is CTLA4; the disease is hereditary elliptocytosis.