Based on the results of reference analysis and keyword extraction, those dominating were “apoptosis”, “insulin resistance”, “encephalopathy”, “IFN-γ” and others mentioned in the top-ranked items may have been popular research topics over the past years but may have slowed down with the development of other novel directions such as “papillary thyroid cancer”, “Vitamin D”, “oxidative stress”, “polymorphism” and “association”. The gene discussed is IFNG; the disease is thyroid gland papillary carcinoma.