Compared with other clinicopathological parameters, including Lauren subtype, gender, age, tumor size (T), lymph node metastasis (N), distant metastasis (M), TNM stage, tumor differentiation, preoperative serum carcinoembryonic antigen (CEA) levels, and preoperative serum carbohydrate antigen 19-9 (CA19-9) levels, univariate Cox regression revealed that the TIIC groups were indeed prognostic factors for gastric cancer (Supplementary Figure 2B). Here, CEACAM5 is linked to gastric cancer.