POSTN and neoplasm: In vitro studies revealed that CSCs can have a role in monocyte recruitment across tumor types, as supernatants from patient-derived cholangiocarcinoma, hepatocellular carcinoma, or glioblastoma sphere cultures, enriched in CSCs, displayed higher levels of pro-tumoral chemokines, cytokines, growth factors, signaling molecules, and including CCL2, CCL5, CSF1, IL-13, periostin, and WISP1 if compared with their non-CSC counterparts (132–134).