ACLY and systemic lupus erythematosus: The classification criteria for APS (5) include lupus anticoagulant (LAC), as well as the IgG and IgM isotypes of anti-cardiolipin (aCL) and anti-beta2-glycoprotein 1 (aB2GP1), while some classification criteria for SLE include also the IgA isotypes (6–8).