PFKFB3 and neoplasm: In contrast, most tumor tissues demonstrated higher expression of glucose transporter 1 (GLUT1) (with significance) together with superior levels of its downstream molecules 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase 3 (PFKFB3), pyruvate kinase M (PKM), and lactate dehydrogenase A (LDHA) (trend only) (Figure 1A, lower panel).