Apart from MDS, ZRSR2 mutations have also been reported in other hematological malignancies including chronic myelomonocytic leukemia (CMML) [3], myeloproliferative neoplasms (MPN) [3], and blastic plasmacytoid dendritic cell neoplasm (BPCDN) [8]. This evidence concerns the gene ZRSR2 and chronic myelomonocytic leukemia.