We identified two TRIOBP frameshift variants in this individual, heterozygous c.572delC p.Pro191Argfs*50, as well as a heterozygous insertion, c.3510_3513dupTGCA, p.Pro1172Cysfs*13 which demonstrated perfect segregation with the deafness phenotype (Figure 1) on segregation analysis (Figure 1). This evidence concerns the gene TRIOBP and deafness.