Furthermore, CRP in the vaccinated COVID‐19 patients in the third wave was significantly higher than in vaccinated COVID‐19 patients (2.83 ± 2.21), pv ≤ 0.0001) and unvaccinated COVID‐19 patients (3.67 ± 2.60, pv < 0.0001) in 4th wave of the pandemic. This evidence concerns the gene CRP and COVID-19.