CRP in vaccinated COVID‐19 patients (8.43 ± 17.48) was significantly (pv = 0.01) higher than in unvaccinated COVID‐19 patients (6.14 ± 3.27) in the 3rd wave of the pandemic, but there were no significant differences of CRP between vaccinated and unvaccinated COVID‐19 patients in a later wave of the disease. This evidence concerns the gene CRP and COVID-19.