Bhargava et al. [118] stated that the isolated artepillin C from Brazilian green propolis abrogated mortalin-p53 complex, causing the activation of p53 and the growth arrest of cancer cells at 275 μM concentration in HT1080 (fibrosarcoma), A549 (lung carcinoma) and U2OS (osteosarcoma) human cell lines. This evidence concerns the gene TP53 and cancer.