In tumor tissues where the vascular regulation imbalance exists [4, 5], the related cytokines Angiogenin-2 (ANG-2) and vascular endothelial growth factor (VEGF) are overexpressed to promote the pathological angiogenesis particularly in the early period of the tumor progression, which are immature and leaky blood vessels [6, 7]. Here, VEGFA is linked to neoplasm.