MAP3K7 and myelodysplastic syndrome: As shown in Fig. 7a, the expression levels of MAP3K7 and ABCB7 were lower in SF3B1MUT-MDS patients than in SF3B1WT-MDS patients, although not significantly lower for ABCB7. On the other hand, there was no difference in the expression levels of ABCB7 and MAP3K7 between MDS-RS and non MDS-RS patients (see Supplementary Fig. S26 online), indicating a greater contribution of SF3B1 mutation status, rather than RS existence, to the regulation of ABCB7 and MAP3K7 expression.