AKR1B10P1, an isoform pseudogene of oncogenic AKR1B10, is validated as a down-stream target degraded by tumor-suppressing miR-138, and there existed a positive feedback from AKR1B10P1, by which miR-138 interacts with AKR1B10P1 via a ceRNA approach in HCC [27]. Here, AKR1B10 is linked to hepatocellular carcinoma.