The aim of the present study was to determine whether the -493G/T (rs1800591), I128T (rs3816873), Q95H (rs61733139), and Q244E (rs17599091) Single Nucleotide Polymorphisms (SNPs) in the MTTP gene are linked to the presence of hepatic steatosis in patients with chronic hepatitis C. This evidence concerns the gene MTTP and chronic hepatitis C virus infection.