However, to date, HER2 diagnostic criteria for gastroesophageal adenocarcinoma (GEA criteria) (Richman et al. 2016) or other independent HER2 IHC scoring systems (Shabbir et al. 2016; Moussa et al. 2020) have also been used in CRC HER2 studies. Here, ERBB2 is linked to colorectal carcinoma.