A long non-coding RNA (lncRNA) named CAHM (chr6: 163,834,097–163,834,982), located adjacent to the QKI gene, has been demonstrated to be specifically hypermethylated in CRC and adenoma, with a low methylation level in the tissue of lung, prostate, and breast cancers (Pedersen et al., 2014). Here, QKI is linked to colorectal carcinoma.