Nevertheless, patients with corona virus disease 2019 (COVID-19) not only show lower proportions of SARS-CoV-2-specific CD4+ or CD8+ T cells but also B cells and NK cells, with increasing disease severity (Huang et al., 2020; Peng et al., 2020; Zeng et al., 2020; Olea et al., 2021). Here, CD8A is linked to COVID-19.