SOD1 and Alzheimer disease: Moreover, the use of Lactobacillus and Bifidobacterium can reduce Aβ deposition in the brain of rats injected with Aβ42 in the hippocampus, promote superoxide dismutase (SOD) production, and reduce serum malondialdehyde (MAD) levels, so Lactobacillus and Bifidobacterium Bacillus can improve AD memory, learning deficits and oxidative stress [40].