MUC1 and familial pancreatic carcinoma: According to Jeong et al. (2018), the inhibitory effect of threonine deprivation on the migration of pancreatic cancer cells depended on MUC1 (Mucin1), a threonine-rich oncoprotein upregulated in several types of cancer, which contributed to neoplastic transformation, tumor associated angiogenesis and metastasis (Kufe, 2009).