The potential protective effect of SGLT2 inhibitors in COVID-19 may be associated with multiple pleiotropic properties, including anti-inflammatory action and a decrease in the severity of oxidative stress, improved myocardial and endothelial function, improved oxygen delivery, and increased urine output (36) and with a well-known cardio- and nephroprotective effect of this class of drugs (37). Here, SLC5A2 is linked to COVID-19.