The results of the ELISA assay showed that PSG significantly reduced the high levels of IL-1β and IL-18 in the livers of DSS-induced IBD mice (Figures 6(a) and 6(b)), and IHC staining indicated that DSS increased the expression of NLRP3 while PSG reversed it (Figure 6(c)). The gene discussed is NLRP3; the disease is inflammatory bowel disease.