The mechanism of [18F]-PSMA expression and/or [18F]-PSMA ligand accumulation in inflammatory and infectious processes is not well understood, and only a few studies on this topic are available.10 There is some evidence that increased [18F]-PSMA expression during neovascularization,11 accumulation of [18F]-PSMA ligands at the infection site10 and the interference of macrophage folate receptors with [18F]-PSMA ligands12 may play a role in inflammatory and infectious processes. Here, FOLH1 is linked to infection.