A positive relation was detected between the FUNDC1 expression and the degree of B cell infiltration (r = 0.429, p = 8.38e − 17), macrophages (r = 0.513, p = 2.89e − 24), neutrophils (r = 0.457, p = 3.63e − 19), DCs (r = 0.448, p = 3.59e − 18), CD8+ T cells (r = 0.336, p = 1.71e − 10), and CD4+ T cells (r = 0.391, p = 4.80e − 14) in HCC but no correlation with tumor purity (r = −0.027, p = 6.15e − 01) (Figure 8). Here, CD4 is linked to neoplasm.