Additionally, we performed a functional analysis of the NRGs, and our results indicated that these NRGs were involved in platinum drug resistance, bladder cancer, apoptosis, p53 signaling pathway, pancreatic cancer, hepatitis B, erbB signaling pathway, apoptosis-multiple species, IL-17 signaling pathway, and endocrine resistance. This evidence concerns the gene TP53 and familial pancreatic carcinoma.