NRGs were found to be associated with the following KEGG pathways: platinum drug resistance, bladder cancer, apoptosis, p53 signaling pathway, pancreatic cancer, hepatitis B, erbB signaling pathway, apoptosis-multiple species, interleukin 17 (IL-17) signaling pathway, and endocrine resistance (Figure 2A). The gene discussed is TP53; the disease is hepatitis B virus infection.