MBL2 and viral infectious disease: Innate immune system components of either secreted (e.g., type I interferons, IFNs), membrane-bound (e.g., toll-like receptors; TLRs, mannose-binding lectin; MBL) or cytoplasmic (e.g., DNA cytoplasmic sensors) nature, are responsible for sensing and containment of the viral infection during the lag phase needed for adaptive immunity to become operative (9, 10).