BCR and B-cell chronic lymphocytic leukemia: Figure 6 shows representative super resolution images of IgG M-CLL, IgM M-CLL, and IgM U-CLL subgroups. Whereas IgG M-CLL (Figures 6A, B) and IgM M-CLL (Figures 6D, E) display labeling restricted to the membrane plane of the cells, in IgM U-CLL, labeling is also observed within the cells, as indicated by the signal located in the central part of the cells (Figures 6G, H). Representative 3D reconstructions demonstrate the differences of the basal BcR distribution between IgM U-CLL (Supplementary Movie S1), IgM M-CLL (Supplementary Movie S2), and IgG M-CLL (Supplementary Movie S3).