Based on some research, microRNA-375 (miR-375), microRNA-218-5p (miR-218-5p), and miR-185 attenuated oxidative stress, as evidenced by elevated SOD and GPx activity in PD rats treated with these miRNAs (Cai et al., 2020; Ma et al., 2021b; Qin et al., 2021). The gene discussed is SOD1; the disease is Parkinson disease.