MMP2 and neoplasm: As revealed in Figure 7, the expression of phosphorylated FAK was inhibited by cratoxylumxanthone C, and the expression of FAK was unchanged after treatment with cratoxylumxanthone C. Matrix metallopeptidase 2 (MMP2) is a key protein of FAK signal pathway, and the MMP2 levels are usually considered to be a indicator of tumor metastasis.